Seems MaxTenuringThresholdConstraintFunc, InitialTenuringThresholdConstraintFunc and AllocatePrefetchStepSizeConstraintFunc check uint values (see gc_globals.hpp). However those functions have uintx in the check functions.
This causes Ubsan to complain :

/jdk/src/hotspot/share/runtime/flags/jvmFlagAccess.cpp:176:12: runtime error: call to function MaxTenuringThresholdConstraintFunc(unsigned long, bool) through pointer to incorrect function type 'JVMFlag::Error (*)(unsigned int, bool)'
jvmFlagConstraintsGC.cpp:188: note: MaxTenuringThresholdConstraintFunc(unsigned long, bool) defined here
    #0 0x10541cfbe in FlagAccessImpl_uint::typed_check_constraint(void*, unsigned int, bool) const jvmFlagAccess.cpp:176
    #1 0x1054253d7 in JVMFlagLimit::check_all_constraints(JVMFlagConstraintPhase) jvmFlagLimit.cpp:179
    #2 0x105f20b98 in Threads::create_vm(JavaVMInitArgs*, bool*) threads.cpp:471
    #3 0x10538c3fb in JNI_CreateJavaVM_inner(JavaVM_**, void**, void*) jni.cpp:3581
    #4 0x10342e71c in JavaMain java.c:491
    #5 0x103435248 in ThreadJavaMain java_md_macosx.m:720
    #6 0x7fff204338fb in _pthread_start+0xdf (libsystem_pthread.dylib:x86_64+0x68fb)
    #7 0x7fff2042f442 in thread_start+0xe (libsystem_pthread.dylib:x86_64+0x2442)

/jdk/src/hotspot/share/runtime/flags/jvmFlagAccess.cpp:176:12: runtime error: call to function InitialTenuringThresholdConstraintFunc(unsigned long, bool) through pointer to incorrect function type 'JVMFlag::Error (*)(unsigned int, bool)'
jvmFlagConstraintsGC.cpp:177: note: InitialTenuringThresholdConstraintFunc(unsigned long, bool) defined here
    #0 0x117b1cfbe in FlagAccessImpl_uint::typed_check_constraint(void*, unsigned int, bool) const jvmFlagAccess.cpp:176
    #1 0x117b253d7 in JVMFlagLimit::check_all_constraints(JVMFlagConstraintPhase) jvmFlagLimit.cpp:179
    #2 0x118620b98 in Threads::create_vm(JavaVMInitArgs*, bool*) threads.cpp:471
    #3 0x117a8c3fb in JNI_CreateJavaVM_inner(JavaVM_**, void**, void*) jni.cpp:3581
    #4 0x10077e71c in JavaMain java.c:491
    #5 0x100785248 in ThreadJavaMain java_md_macosx.m:720
    #6 0x7fff204338fb in _pthread_start+0xdf (libsystem_pthread.dylib:x86_64+0x68fb)
    #7 0x7fff2042f442 in thread_start+0xe (libsystem_pthread.dylib:x86_64+0x2442)

and

/jdk/src/hotspot/share/runtime/flags/jvmFlagAccess.cpp:157:12: runtime error: call to function AllocatePrefetchStepSizeConstraintFunc(long, bool) through pointer to incorrect function type 'JVMFlag::Error (*)(int, bool)'
jvmFlagConstraintsCompiler.cpp:70: note: AllocatePrefetchStepSizeConstraintFunc(long, bool) defined here
    #0 0x10239bcee in FlagAccessImpl_int::typed_check_constraint(void*, int, bool) const jvmFlagAccess.cpp:157
    #1 0x1023a53d7 in JVMFlagLimit::check_all_constraints(JVMFlagConstraintPhase) jvmFlagLimit.cpp:179
    #2 0x102ee640b in universe_init() universe.cpp:875
    #3 0x10213ee27 in init_globals() init.cpp:128
    #4 0x102ea0d69 in Threads::create_vm(JavaVMInitArgs*, bool*) threads.cpp:553
    #5 0x10230c3fb in JNI_CreateJavaVM_inner(JavaVM_**, void**, void*) jni.cpp:3581
    #6 0x10041271c in JavaMain java.c:491
    #7 0x100419248 in ThreadJavaMain java_md_macosx.m:720
    #8 0x7fff204338fb in _pthread_start+0xdf (libsystem_pthread.dylib:x86_64+0x68fb)
    #9 0x7fff2042f442 in thread_start+0xe (libsystem_pthread.dylib:x86_64+0x2442)